The Addicks return to SE7 for their first time since March as Queens Park Rangers provide the first test for Lee Bowyer's men behind closed doors at The Valley (12.30pm).
Charlton will be looking to build on the positivity of last weekend's victory at Hull City, which saw them begin the Championship restart by climbing back out of the bottom three with a vital three points.
QPR, meanwhile, head to south London off the back of a 1-0 defeat to second-from-bottom Barnsley at Loftus Road.
Bowyer revealed that he has no fresh injury concerns following last weekend's trip to Hull and he welcomes back Andre Green and Jake Forster-Caskey into the squad following niggles, as well as George Lapslie, who missed the journey north due to the birth of his daughter.
However, the Addicks will still be without Lewis Page and Manchester City loanee Matt Smith, although they are expected to return soon.
QPR are without captain Grant Hall who turned down a contract extension and made himself unavailable, while Marc Pugh is also unavailable after being released by the club.
Geoff Cameron will be available again after serving a suspension against Barnsley last weekend.
Charlton Boss Lee Bowyer: “That three points is going to make a big difference to us on confidence. It maybe just shows that we aren’t a bad side, because we weren’t on the best of runs. But we’ve come back looking good and, hopefully, we can pick up more wins like we did at the weekend."
Queens Park Rangers boss Mark Warburton: "As a team we let ourselves down [against Barnsley]. It was a heated dressing room and quite rightly because we dropped three valuable points. We had to manage the game better - we were really poor for the first 45 minutes, were 1-0 down and it could have been two."
Charlton and QPR have met on 69 previous occasions with the Addicks winning 24 and QPR coming out on top 23 times, with the remaining 22 games ending in draws.
One of those draws came in the last meeting between the two sides when Naby Sarr's late, late equaliser earned a point at Loftus Road in December.
Charlton have won the last two meetings in SE7 - a 2-0 win in August 2015 and a memorable 1-0 victory in February 2014 which saw Johnnie Jackson net a stoppage-time winner in front of the Covered End.
Darren England will be the man in the middle for Saturday's game in SE7. He has taken charge of 27 games during the 2019/20 season, dishing out 82 yellow cards and just one red.
It will be the third time he has refereed the Addicks this term. His first was during the 1-0 win over Brentford at The Valley in August and his second was the 3-1 defeat at the hands of Sheffield Wednesday in November.
All of the remaining games of the 2019/20 season are being played behind closed doors and supporters are reminded to maintain social distancing guidelines and to stay away from stadiums when matches are taking place.
Supporters can follow all the build-up to the game on Charlton's official Instagram account, official Twitter account and Facebook page as usual. Supporters both in the UK and abroad are able to watch the game live on Valley Pass which includes a multi-camera broadcast, action replays and commentary from Terry Smith and Greg Stubley, the club's in-house commentary team.
Supporters who live abroad will be able to watch the game for the usual price of £5, while supporters in the UK and Ireland can purchase a game pass for £10 which is the minimum the club are allowed to charge due to EFL regulations.
Supporters who have already purchased a multi-game package will have been sent a code to access Saturday's game.
Meanwhile, live audio commentary of the game from Smith and Stubley will be available to Valley Pass subscribers in all countries as usual.