Akin Famewo and Ben Watson will start for Charlton as Nigel Adkins makes two changes from the team that drew with Ipswich Town at the weekend, for tonight's game against Plymouth Argyle.
12-goal Chuks Aneke returns to the bench after missing the last two games with a minor injury.
Famewo takes the place of Ryan Inniss who is rested after playing every minute of the last three games following more than four months on the sidelines.
Watson, who made a noticeable difference from the bench on Saturday, starts in place of Darren Pratley.
If the Addicks line-up in the same 4-3-3 used in the previous three games then Adam Matthews, Famewo, skipper Jason Pearce and Ben Purrington will make up the back four in front of Ben Amos. Watson will look to control the midfield alongside Jake Forster-Caskey and Alex Gilbey.
Diallang Jaiyesimi and Liam Millar are expected to operate from the wings either side of Jayden Stockley.
Pratley and Aneke are joined on the bench by Ashley Maynard-Brewer, Chris Gunter, Deji Oshilaja, Albie Morgan and Andrew Shinnie.
Charlton: Amos; Matthews, Famewo, Pearce (C), Purrington; Gilbey, Watson, Forster-Caskey; Jaiyesimi, Stockley, Millar
Substitutes: Maynard-Brewer, Gunter, Oshilaja, Pratley, Morgan, Shinnie, Aneke