Luke Berry will make his first start of the season as the Addicks travel to Stoke City (KO 7.45pm BST).
James Bree, who wasn’t eligible for Saturday’s game against his parent club Southampton, also returns to the starting XI as Nathan Jones makes two changes.
There is also a place on the substitutes bench for Amari’i Bell, who is in the squad for the first time since limping off against Swansea City at The Valley earlier this month.
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Kayne Ramsay, Lloyd Jones, Macaulay Gillesphey start in a back three in front of Thomas Kaminski.
Should the Addicks play in the five-box-one formation used against Wrexham then Bree and Tyreece Campbell would operate as wing-backs. Berry would likely join Conor Coventry, skipper Greg Docherty and Sonny Carey in a box midfield behind Miles Leaburn.
Bell is joined on the bench by Will Mannion, Keenan Gough, Karoy Anderson, Joe Rankin-Costello, Harvey Knibbs, Rob Apter, Ibrahim Fullah and Tanto Olaofe.
Charlton: Kaminski; Ramsay, Jones, Gillesphey; Bree, Coventry, Docherty (c), Campbell; Carey, Berry; Leaburn
Subs: Mannion, Gough, Bell, Anderson, Rankin-Costello, Knibbs, Apter, Fullah, Olaofe
