The Addicks will be looking to make it five consecutive wins for the first time since 2012 as they head to Kenilworth Road to take on Luton Town on Saturday afternoon.
Lee Bowyer's men have seen off Southend United, Wycombe Wanderers, Bradford City and Plymouth Argyle in recent weeks to climb into the top six and will hope to cement that place in the play-off pack with an eye on the top two from a first league trip to the Bedfordshire club since October 1995.
The Hatters, meanwhile, sit in 12th position with three wins, three draws and three defeats since winning promotion to the third tier last term.
Bowyer has confirmed that Darren Pratley will return to the squad having sat out of the last two games with injury, while Tariqe Fosu is available once again having served a three-match ban following his dismissal against Southend.
However, the trip to Kenilworth Road will come too soon for Krystian Bielek and Billy Clarke, while Patrick Bauer will remain unavailable, as will long-term absentee Jake Forster-Caskey.
Danny Hylton is a doubt for the Hatters, while Luke Berry remains in the treatment room having suffered a broken leg last season. Former Addick Alan McCormack is likely to be available for selection again.
The Addicks will have over 1000 supporters backing them at Kenilworth Road and all away tickets for the match are SOLD OUT.
Charlton boss Lee Bowyer: “Luton are a good side. They’ve spent wisely this summer. I think they’ve brought in some good players, and I was surprised how good they were really, but it’s going to be tough going there, for sure.
“They move the ball well, they compete, they press high and they get bodies in the box. They’re the team to do that, so they’re dangerous.”
Luton boss Nathan Jones: “It's a tough game. They're a good side, a very good side. The manager has done well there under difficult circumstances, fair play. They're a big club for this level.
"They've got good players and it will be a real good test of us, our structure and where we are because there are sides that are Premiership, or ex-Premiership sides at this level, and they're one of them. it'll be a tough test, but a great test for us.".
Saturday’s game will be the 72nd meeting between the two sides. The Addicks have come out on top on 23 occasions, with the Hatters winning 34 times and the remaining 14 encounters ending in draws.
Charlton's last visit to Kenilworth Road came in an FA Cup second-round replay in December 2011 in which Scott Wagstaff, Joe Anyinsah and Johnnie Jackson netted in a 3-1 victory.
It has been 23 years since the two club's met in this fixture in the league, with Garry Nelson netting the only goal in a 1-0 victory for the Addicks in October 1995.
Antony Coggins will take charge of Saturday's clash. He has refereed nine games so far this season, producing 38 yellow cards and one red.
He was the man in the middle for Charlton's goalless draw with Fleetwood Town at The Valley last month, in which he showed seven yellow cards, of which Patrick Bauer, Naby Sarr and Darren Pratley were cautioned.
Supporters can follow all the build-up to the game on Charlton's official Instagram account, official Twitter account, Facebook page and official Snapchat account.
Live commentary of the clash will be available on Valley Pass exclusively for subscribers. Please click here for more information on how you can subscribe to Valley Pass and how you can purchase a 48-hour matchday pass, which is priced at just £4.