Charlton Athletic host Huddersfield Town under the lights at The Valley on Tuesday night hoping that they can break a difficult spell.
The Addicks narrowly lost 1-0 to Middlesbrough at the weekend and Bowyer has insisted that his side will be "fiery and up for it" when the Terriers make the trip to the capital.
Huddersfield themselves have endured a rude awakening upon their return to the Championship from the Premier League, sitting in 21st, just two points above the relegation zone.
Lee Bowyer said that the only positive from the performance at the weekend was the return of striker Lyle Taylor and he will again look to play the forward as he builds up on his match fitness, most likely from the bench.
Chuks Aneke's setback means he will not feature, nor will Tomer Hemed, still leaving Charlton short in the frontline department.
Jonny Williams returned to training on Monday, but Tuesday's match will come too soon. Josh Cullen, Jake Forster-Caskey, Sam Field, Beram Kayal, and George Lapslie will remain sidelined. Lewis Page also remains injured in the defence but Tom Lockyer is cleared to play again having served his one-match ban.
Maynard-Brewer is expected to continue his place on the bench as Ben Amos still recovers from surgery.
The visitors will have their own selection concerns with Trevoh Chalobah unavailable with a three-match ban while Fraizer Campbell, Danny Simpson, Jaden Bowen, Lewis O'Brien and Alex Pritchard may struggle to feature through injuries.
Charlton captain Jason Pearce: “Whenever you have a bad performance or a bad result, it’s always good to have a game straight away, so that’s a positive.
“On behalf of the players, I thank the fans that travelled up [to Middlesbrough] and apologise for the performance. It obviously wasn’t good enough and they’ve travelled a long away to watch us and support us. We’ll do our best as a team and as a squad to try and put that right on Tuesday. We’ll keep fighting and fighting for the shirt and doing our best.”
Huddersfield Town boss Danny Cowley: “Charlton are a different team and proposition on Tuesday night, but we will still have to adapt. We will find the best way of playing with the group we have available. It’s a tough moment, but we’re doing our collective best to navigate through the situation."
The Addicks and the Terriers have battled it out 90 times in the past with Charlton emerging victorious on 37 occasions, drawing 19 games and losing 34.
Charlton's last win came at The Valley in February 2015 when a Tony Watt brace and a wonderful free-kick from Johann Berg Gudmundsson earned the Addicks a 3-0 win.
Graham Scott will be the man in charge of the contest. Scott has overseen 12 games this season - 10 of them in the Premier League - and has handed out 35 yellow cards and three reds.
Neil Davis and Harry Lennard will join him as the assistant referees while David Rock will be the Fourth Official.
Supporters purchasing concession tickets should be aware that ID checks will be in place for those who may appear close to, or outside, the relevant age groups. Appropriate identification includes a driving license, passport or any other photographic ID that shows date of birth. The club will also accept a copy/photograph of these documents provided the date of birth is clearly legible.
Supporters are advised to get to the ground early to avoid queuing to get into the ground. Supporters are also asked to not bring bags, if possible, to help speed up the bag search process.
A 'print at home' option is available, or tickets can be scanned from mobile devices. Tickets are available from the stadium on the day, but supporters should note that a £3 increase on adult, over 65s and U21 tickets kick in 2 hours before kick off.
Supporters can follow all the build-up to the game on Charlton's official Instagram account, official Twitter account and Facebook page.
Live commentary of the clash - presented by ITRM - will be available on Valley Pass exclusively for subscribers. You can subscribe to Valley Pass or purchase a 48-hour matchday pass, which is priced at just £4.
Domestic fans can watch the game for £10 on Valley Pass, which is the minimum price clubs are allowed to charge for midweek fixtures by the EFL.
International fans can watch the game with a Match Pass which costs £5 or supporters can buy a Season Pass for £110 which offers the best value for money.